{"id":101,"date":"2015-04-08T21:53:58","date_gmt":"2015-04-08T19:53:58","guid":{"rendered":"http:\/\/imuna.sk\/?page_id=101"},"modified":"2019-10-16T15:20:08","modified_gmt":"2019-10-16T13:20:08","slug":"vyskum-a-vyvoj","status":"publish","type":"page","link":"https:\/\/www.imuna.sk\/en\/vyskum-a-vyvoj\/","title":{"rendered":"Research and Development"},"content":{"rendered":"<p>The <strong>primary goal<\/strong> of the Research and Development Department is to bring safe, modern and affordable pharmaceuticals to the Slovak and international market, in accordance with IMUNA PHARM a.s. company vision.<\/p>\n<p>The aim of the Research and Development Department is to create an internationally recognized research unit with state-of-the-art equipment for applied research and development, to support the scientific potential of young and talented scientists, as well as to promote cooperation between IMUNA PHARM, a.s. and the academic sector on applied research projects and the development of new technologies on an international level. To foster this aim, the Research and Development Department employs research and development professionals with various educations, experience and nationalities.<\/p>\n<p>The IMUNA PHARM, a.s. Research and Development Department focuses its activities on innovating its current portfolio of products and the development of new drugs to combat communicable diseases, these being not only vaccines, but also immunomodulatory preparations, allergens, probiotics and bacteriophages.<\/p>\n<p><strong>Projects of the<\/strong> Research and Development Department include:<\/p>\n<ul>\n<li>Development and manufacture of new product stabilizers and product formulas to increase their safety and ease of application by the patient,<\/li>\n<li>Development and implementation of modern technological manufacturing processes in cooperation with the Production Department,<\/li>\n<li>Development of new analytic methods to test drug safety and efficacy in compliance with the European Pharmacopoeia and WHO regulations, in cooperation with the Quality Control Department,<\/li>\n<li>Development of new animal models to be used in pre-clinical trials for biologically active substances and for testing their efficacy,<\/li>\n<li>Research in new biologically active substances using state-of-the-art modern technology,<\/li>\n<li>Research and development of new and innovative cell substrates, and implementing new technologies in vaccine production.<\/li>\n<\/ul>\n<h2>Research Cooperation<\/h2>\n<p>The Research and Development Department is the principal investigator in several basic and applied projects co-financed by the Ministry of Education, Science, Research and Sport of the Slovak Republic and the European Regional Development Fund (link to Projects &amp; Grants tab). The Department is also an active long-term partner of the academic sector in basic and applied research projects, not only in Slovakia but also in the Czech Republic and other countries.<\/p>\n<p><h2><a href=\"#publications\" data-toggle=\"collapse\" aria-expanded=\"false\" aria-controls=\"publications\">Publications<\/a><\/h2><div class=\"collapse product-group\" id=\"publications\"><strong><em>2013<\/em><\/strong><\/p>\n<p>T . Betakova, D. Svetlikova, M. Gocnik, Overview of measles and mumps vaccine: origin, present and future of vaccine production, Acta Virol, ISSN: 0001-723X, 2013;57(2):91-6<\/p>\n<p>M. Miklo\u0161ov\u00e1, Viral Vaccines \u2013 optimizing their stability and efficacy, Farmaceutick\u00fd obzor, ISSN: 0014-8172, LXXXII, 2013, 11-12, 288-292<\/p>\n<p>M. Miklo\u0161ov\u00e1, V\u00edrusov\u00e9 vakc\u00edny \u2013 optimaliz\u00e1cia ich stability a efekt\u00edvnosti (Virus Vaccines \u2013 optimalization of stability and efficacy), Lek\u00e1rske Listy &#8211; Pediatria, 2013, 35, 18-20<\/p>\n<p>M. Miklo\u0161ov\u00e1, V\u00fdskum nov\u00fdch fin\u00e1lnych foriem v\u00edrusov\u00fdch vakc\u00edn s cie\u013eom optimaliz\u00e1cie ich stability (Research in new final forms of virus vaccines in order to optimalize their stability), Zdravotn\u00edcke noviny, 2013, December<\/p>\n<p><strong><em>2014<\/em><\/strong><\/p>\n<p>M. Tomkov\u00e1, T. Ka\u0161ko, M. Bubanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, Optimization of conditions for various cell substrates growth for future vaccine production and assay development, Abstracts of EATB 2014 Annual Meeting, 2014, p28<\/p>\n<p>T. Ka\u0161ko, I. Jakubec, M. Handl, J. Adler, Autologous cultured chondrocytes for the treatment of articular cartilage defects, Abstracts of EATB 2014 Annual Meeting, 2014, p5<\/p>\n<p><strong><em>2015<\/em><\/strong><\/p>\n<p>F.M.Lopez Cardoso, D. Petrovajov\u00e1, M. Bubanov\u00e1, I. Lojanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, Improving stability of measles and mumps vaccine by replacing human serum albumin with amino acids mixes, Abstracts from Vaccines 2014 meeting, The Biomedical Scientist, 2015 &#8211; accepted<\/p>\n<p>F.M.Lopez Cardoso, D. Petrovajov\u00e1, M. Bubanov\u00e1, I. Lojanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, Zlep\u0161enie stability vakc\u00edn proti mumpsu a os\u00fdpkam z\u00e1menou \u013eudsk\u00e9ho s\u00e9rov\u00e9ho album\u00ednu za zmes aminokysel\u00edn (Improving stability of measles and mumps vaccine by replacing human serum albumin with amino acids mixes), Zborn\u00edk abstraktov z predn\u00e1\u0161ok VI. Slovensk\u00fd vakcinologick\u00fd kongres, ISBN: 978-80-971836-3-9, 2015, January<\/p>\n<p>E. Baj\u00fasov\u00e1, T. Hor\u0148\u00e1kov\u00e1, Potencovanie \u00fa\u010dinnosti hum\u00e1nnych a veterin\u00e1rnych vakc\u00edn adjuvansami (Improving the efficiency of human and veterinary vaccines with adjuvants), Medical Practice, 2015, February<\/p>\n<p>E. Baj\u00fasov\u00e1, T. Hor\u0148\u00e1kov\u00e1, Potencovanie \u00fa\u010dinnosti hum\u00e1nnych a veterin\u00e1rnych vakc\u00edn adjuvansami (Improving the efficiency of human and veterinary vaccines with adjuvants), Zborn\u00edk abstraktov z predn\u00e1\u0161ok VI. Slovensk\u00fd vakcinologick\u00fd kongres, ISBN: 978-80-971836-3-9, 2015, January<\/p>\n<p><strong><em>2016<\/em><\/strong><\/p>\n<p>Stanovenie obsahu stabiliz\u00e1toru \u013eudsk\u00e9ho s\u00e9rov\u00e9ho album\u00ednu (HSA) v lyofilizovanej monovakc\u00edne proti mumpsu a os\u00fdpkam met\u00f3dou ELISA. Bubanov\u00e1 M., Lopez Cardoso M. F., Tomkov\u00e1 M., T. Hor\u0148\u00e1kov\u00e1, Zborn\u00edk abstraktov z predn\u00e1\u0161ok VII. Slovensk\u00fd vakcinologick\u00fd kongres, ISBN: 978-80-89797-08-0, 2016, January<\/p>\n<p>Genome stability of the Jeryl Lynn derived Pavivac mumps virus vaccine strain and vaccine safety, Tomkov\u00e1 M., Labudov\u00e1 M., Lopez Cardoso F.M., Pantula V., Zeln\u00edk V., Miklo\u0161ov\u00e1 M., Hor\u0148\u00e1kov\u00e1 T. a Kopa\u010dek J., Zborn\u00edk abstraktov z predn\u00e1\u0161ok VII. Slovensk\u00fd vakcinologick\u00fd kongres, ISBN: 978-80-89797-08-0, 2016, January<\/p>\n<\/div>\n<p><h2><a href=\"#presentations\" data-toggle=\"collapse\" aria-expanded=\"false\" aria-controls=\"presentations\">Presentations<\/a><\/h2><div class=\"collapse product-group\" id=\"presentations\"><strong><em>2014<\/em><\/strong><\/p>\n<p>Optimization of conditions for various cell substrates growth for future vaccine production and assay development, <u>M. Tomkov\u00e1<\/u>, T. Ka\u0161ko, M. Bubanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, EATB 2014, The 23rd Annual Congress of the European Association of Tissue Banks, Lund, Sweden, 1-3 October 2014 &#8211; poster presentation<\/p>\n<p>Autologous cultured chondrocytes for the treatment of articular cartilage defects, <span style=\"text-decoration: underline;\">T. Ka\u0161ko<\/span>, I. Jakubec, M. Handl, J. Adler, The 23rd Annual Congress of the European Association of Tissue Banks, Lund, Sweden, 1-3 October 2014 &#8211; <span style=\"text-decoration: underline;\">poster presentation<\/span><\/p>\n<p>Improving stability of measles and mumps vaccine by replacing human serum albumin with amino acids mixes, <span style=\"text-decoration: underline;\">F.M.Lopez Cardoso<\/span>, D. Petrovajov\u00e1, M. Bubanov\u00e1, I. Lojanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, The Vaccines congress, London, UK, 20-22 October 2014 &#8211; <span style=\"text-decoration: underline;\">oral presentation<\/span><\/p>\n<p><strong><em>2015<\/em><\/strong><\/p>\n<p>Zlep\u0161enie stability vakc\u00edn proti mumpsu a os\u00fdpkam z\u00e1menou \u013eudsk\u00e9ho s\u00e9rov\u00e9ho album\u00ednu za zmes aminokysel\u00edn (Improving stability of measles and mumps vaccine by replacing human serum albumin with amino acids mixes), F.M.Lopez Cardoso, <span style=\"text-decoration: underline;\">D. Petrovajov\u00e1<\/span>, M. Bubanov\u00e1, I. Lojanov\u00e1, T. Hor\u0148\u00e1kov\u00e1, VI. Slovensk\u00fd vakcinologick\u00fd kongres, \u0160trbsk\u00e9 Pleso, SR, 15-17 Janu\u00e1r 2015 \u2013 <span style=\"text-decoration: underline;\">poster presentation<\/span><\/p>\n<p>Potencovanie \u00fa\u010dinnosti hum\u00e1nnych a veterin\u00e1rnych vakc\u00edn adjuvansami (Improving the efficiency of human and veterinary vaccines with adjuvants), <span style=\"text-decoration: underline;\">E. Baj\u00fasov\u00e1<\/span>, T. Hor\u0148\u00e1kov\u00e1, VI. Slovensk\u00fd vakcinologick\u00fd kongres, \u0160trbsk\u00e9 Pleso, SR, 15-17 Janu\u00e1r 2015 \u2013 <span style=\"text-decoration: underline;\">poster presentation<\/span><\/p>\n<p>Genome stability of the Jeryl Lynn derived Pavivac mumps virus vaccine strain and vaccine safety, M. Labudov\u00e1, F. M. Lopez Cardoso, V. Pantula, V. Zeln\u00edk, M. Miklo\u0161ov\u00e1, <u>T. Hor\u0148\u00e1kov\u00e1 <\/u>and J. Kopa\u010dek, World Vaccine Congress Europe 2015, Silken Puerta Am\u00e9rica, Madrid, 9 \u2013 11 November 2015 \u2013 <u>poster presentation<\/u><\/p>\n<p><strong><em>2016<\/em><\/strong><\/p>\n<p>Stanovenie obsahu stabiliz\u00e1toru \u013eudsk\u00e9ho s\u00e9rov\u00e9ho album\u00ednu (HSA) v lyofilizovanej monovakc\u00edne proti mumpsu a os\u00fdpkam met\u00f3dou ELISA. <u>Bubanov\u00e1 M<\/u>., Lopez Cardoso M. F., Tomkov\u00e1 M., T. Hor\u0148\u00e1kov\u00e1, VII. Slovensk\u00fd vakcinologick\u00fd kongres, \u0160trbsk\u00e9 Pleso, SR, 14-16 Janu\u00e1r 2016 \u2013 <u>poster presentation<\/u><\/p>\n<p>Genome stability of the Jeryl Lynn derived Pavivac mumps virus vaccine strain and vaccine safety, <u>Tomkov\u00e1 M.<\/u>, Labudov\u00e1 M., Lopez Cardoso F.M., Pantula V., Zeln\u00edk V., Miklo\u0161ov\u00e1 M., Hor\u0148\u00e1kov\u00e1 T. a Kopa\u010dek J., VII. Slovensk\u00fd vakcinologick\u00fd kongres, \u0160trbsk\u00e9 Pleso, SR, 14-16 Janu\u00e1r 2016 \u2013 <u>poster presentation<\/u><\/p>\n<p>Cost effective and robust cell-based assay for Dyalized Leukocyte Extract (DLE)-induced cell viability, <u>Lopez <\/u><u>Cardoso F.M<\/u><u>.<\/u>, Tomkov\u00e1 M., Petrovajov\u00e1 D., Bubanov\u00e1 M., Raga\u010d O., and Hor\u0148\u00e1kov\u00e1 T., X World Congress on Asthma, COPD and Immunopathology, Dubai, UAE, February 6-9, 2016 &#8211; <u>poster presentation<\/u><\/p>\n<p><\/div><\/p>","protected":false},"excerpt":{"rendered":"<p>The primary goal of the Research and Development Department is to bring safe, modern and affordable pharmaceuticals to the Slovak and international market, in accordance with IMUNA PHARM a.s. company vision. The aim of the Research and Development Department is to create an internationally recognized research unit with state-of-the-art equipment for applied research and development, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/pages\/101"}],"collection":[{"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/comments?post=101"}],"version-history":[{"count":25,"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/pages\/101\/revisions"}],"predecessor-version":[{"id":1081,"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/pages\/101\/revisions\/1081"}],"wp:attachment":[{"href":"https:\/\/www.imuna.sk\/en\/wp-json\/wp\/v2\/media?parent=101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}